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Product details

Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL

Catalog number BNC940225-100

Price for BNC940225-100

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Size / count 1x 100 µL

About this product

Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940225-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Lung resistance-related protein (LRP) ; Major Vault Protein; MVP; VAULT1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MVP
Gene ID
9961
NCBI Gene ID
632177
UniProt
Q14764
Swiss Prot
Q14764
Host
Mouse
Species Reactivity
Human
Reactivity
Major Vault Protein
Immunogen
Proteins precipitated from human breast cancer MCF-7 cells
Target Antigen
Major Vault Protein
Clonality
Monoclonal
Clone
1032
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (published)
Field of Research
Cancer, Endocrinology
Positive Control
MCF-7/HeLa, breast tumors
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
104-110 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Mol Cell Proteomics (2013) 12(7): 2006-2020. (WB)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL?

The catalog number for Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL is BNC940225-100.

What sizes are available for Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL in stock?

Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL used for?

Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70%

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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