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Product details

MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL

Catalog number BNC881101-500

Price for BNC881101-500

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Size / count 1x 500 µL

About this product

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881101-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM) ; Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCAM
Gene ID
4162
NCBI Gene ID
599039
UniProt
P43121
Swiss Prot
P43121
Host
Mouse
Species Reactivity
Human
Reactivity
CD146|MCAM|MUC18|Mucin 18
Immunogen
Recombinant human MCAM protein
Target Antigen
CD146 | MCAM | MUC18 | Mucin 18
Clonality
Monoclonal
Clone
MCAM/1101
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
A-375, HUV-EC or HeLa Cells. Tonsil or Melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
130 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL?

The catalog number for MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL is BNC881101-500.

What sizes are available for MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL?

MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL in stock?

MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL?

MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL?

The safety data sheet for MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MCAM / MUC18 / Mucin 18 / CD146 (MCAM/1101), CF488A conjugate, 0.1mg/mL used for?

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metast

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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