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Product details

Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL

Catalog number BNC470702-500

Price for BNC470702-500

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Size / count 1x 500 µL

About this product

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470702-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; TYR; PMEL17
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
2315-MART-1; 7299-Tyrosinase; 6490-gp100
NCBI Gene ID
154069-MART-1; 503555-Tyrosinase; 95972-gp100
UniProt
Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Swiss Prot
Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Host
Mouse
Species Reactivity
Human
Reactivity
Melanoma Marker
Immunogen
Recombinant hMART-1 protein (A103) ; Recombinant tyrosinase protein (T311) ; Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Target Antigen
Melanoma Marker
Clonality
Monoclonal
Clone
HMB45 A103 T311
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer
Positive Control
SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
20-22 kDa (doublet) (MART) ; 70-80 kDa (Tyrosinase) ; 90-100 kDa (gp100)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL?

The catalog number for Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL is BNC470702-500.

What sizes are available for Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL?

Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL in stock?

Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL?

Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ad061270361e108336/msds/bnc470702-500.pdf.

What is Melanoma Marker (HMB45 + A103 + T311), CF647 conjugate, 0.1mg/mL used for?

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melan

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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