Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL

Catalog number BNUB0701-500

Price for BNUB0701-500

Size / count 1x 500 µL

About this product

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB0701-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; TYR; PMEL17
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: 2315-MART-1; 7299-Tyrosinase; 6490-gp100
NCBI Gene ID: 154069-MART-1; 503555-Tyrosinase; 95972-gp100
UniProt: Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Swiss Prot: Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Host: Mouse
Species Reactivity: Human
Reactivity: Melanoma Marker
Immunogen: Recombinant hMART-1 protein (M2-7C10; M2-9E3) ; Recombinant tyrosinase protein (T311) ; Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Target Antigen: Melanoma Marker
Clonality: Monoclonal
Clone: HMB45 M2-7C10 M2-9E3 T311
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer
Positive Control: SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 20-22 kDa (doublet) (MART) ; 70-80 kDa (Tyrosinase) ; 90-100 kDa (gp100)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL?

The catalog number for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL is BNUB0701-500.

What sizes are available for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL in stock?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL?

Estimated delivery time for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL?

The safety data sheet for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 0.2mg/mL used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.