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Product details

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL

Catalog number BNUM0701-50

Price for BNUM0701-50

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Size / count 1x 50 µL

About this product

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0701-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; TYR; PMEL17
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
2315-MART-1; 7299-Tyrosinase; 6490-gp100
NCBI Gene ID
154069-MART-1; 503555-Tyrosinase; 95972-gp100
UniProt
Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Swiss Prot
Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Host
Mouse
Species Reactivity
Human
Reactivity
Melanoma Marker
Immunogen
Recombinant hMART-1 protein (M2-7C10; M2-9E3) ; Recombinant tyrosinase protein (T311) ; Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Target Antigen
Melanoma Marker
Clonality
Monoclonal
Clone
HMB45 M2-7C10 M2-9E3 T311
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer
Positive Control
SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
20-22 kDa (doublet) (MART) ; 70-80 kDa (Tyrosinase) ; 90-100 kDa (gp100)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL?

The catalog number for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL is BNUM0701-50.

What sizes are available for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL in stock?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL?

Estimated delivery time for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL?

The safety data sheet for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1018a3/msds/bnum0701-50.pdf.

What is Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), 1mg/mL used for?

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melan

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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