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Product details

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL

Catalog number BNC040701-500

Price for BNC040701-500

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Size / count 1x 500 µL

About this product

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC040701-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; TYR; PMEL17
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
2315-MART-1; 7299-Tyrosinase; 6490-gp100
NCBI Gene ID
154069-MART-1; 503555-Tyrosinase; 95972-gp100
UniProt
Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Swiss Prot
Q16655-MART-1; P14679-Tyrosinase; P40967-gp100
Host
Mouse
Species Reactivity
Human
Reactivity
Melanoma Marker
Immunogen
Recombinant hMART-1 protein (M2-7C10; M2-9E3) ; Recombinant tyrosinase protein (T311) ; Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Target Antigen
Melanoma Marker
Clonality
Monoclonal
Clone
HMB45 M2-7C10 M2-9E3 T311
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer
Positive Control
SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
20-22 kDa (doublet) (MART) ; 70-80 kDa (Tyrosinase) ; 90-100 kDa (gp100)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL?

The catalog number for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL is BNC040701-500.

What sizes are available for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL in stock?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL?

Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF405S conjugate, 0.1mg/mL used for?

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melan

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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