Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0894-500

Price for BNCB0894-500

Size / count 1x 500 µL

About this product

Anti-PNL2 is a novel monoclonal antibody, which has recently been introduced as an immunohistochemical reagent to stain melanocytes and tumors derived therefrom. The antigen recognized by PNL2 is different from Melan A and gp100. Its epitope is not destroyed by digestion with neuraminidase i.e. its epitope id not glycosylated. Anti-PNL2 may be most useful because of its high sensitivity for metastatic melanoma (87%), as opposed to 76% for anti-HMB45 and 82% for anti-MART-1. Anti-PNL2 labels intra-epidermal nevi while the dermal component of compound nevi are largely non-reactive with anti-PNL2. Antibodies against PNL2, MART-1 (Melan A) and HMB45 stain most clear cell sarcoma cells and a few cells in angio-myolipomas and lymphangioleiomyomatosis. Anti-PNL2 is a useful antibody for the identification of melanomas and clear cell sarcomas. Differential diagnosis is aided by the results from a panel of antibodies, including antibodies against HMB45, MART-1, tyrosinase, and MiTF. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0894-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Human Melanoma Associated Antigen; PNL2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: Not Known
NCBI Gene ID: Not Known
UniProt: Not Known
Swiss Prot: Not Known
Host: Mouse
Species Reactivity: Dog, Human, Mouse
Reactivity: Melanoma Marker
Immunogen: Melanocyte antigen
Target Antigen: Melanoma Marker
Clonality: Monoclonal
Clone: PNL2
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: Melanoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: Multiple (160 kDa, 100 kDa and
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL?

The catalog number for Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL is BNCB0894-500.

What sizes are available for Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL?

Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL in stock?

Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL?

Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Melanoma Marker (PNL2), Biotin conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.