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Product details

MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL

Catalog number BNUB1129-100

Price for BNUB1129-100

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Size / count 1x 100 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1129-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Ia3; Ia-3; H-2Ea; H2-Ea; AI323765; I-Ealpha; E-alpha-f; MHC-H2-Ea
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DPB1
Gene ID
3115 (HLA-DP) & 3122 (HLA-DR)
NCBI Gene ID
347270 (HLA-DP); 520048 (HLA-DR)
UniProt
P04440 (HLA-DP); P01903 (HLA-DR)
Swiss Prot
P04440 (HLA-DP) & P01903 (HLA-DR)
Host
Mouse
Species Reactivity
Human
Reactivity
MHC-II
Immunogen
Human REH cells
Target Antigen
MHC-II
Clonality
Monoclonal
Clone
Bra-14
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Immunology, MHC antigens
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
36 kDa (? chain) and 27 kDa (? chain)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG3, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL?

The catalog number for MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL is BNUB1129-100.

What sizes are available for MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL?

MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL in stock?

MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL?

MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL?

Estimated delivery time for MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL?

The safety data sheet for MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MHC II (HLA-DP) (beta chain) (Bra-14), 0.2mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lympho

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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