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Product details
Catalog number BNC041129-500
Price for BNC041129-500
Size / count 1x 500 µL
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MHC II (HLA-DP) (beta chain) (Bra-14), CF405S conjugate, 0.1mg/mL is BNC041129-500.
MHC II (HLA-DP) (beta chain) (Bra-14), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
MHC II (HLA-DP) (beta chain) (Bra-14), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MHC II (HLA-DP) (beta chain) (Bra-14), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MHC II (HLA-DP) (beta chain) (Bra-14), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MHC II (HLA-DP) (beta chain) (Bra-14), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lympho
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.
Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.
