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Product details

MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL

Catalog number BNC401129-100

Price for BNC401129-100

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Size / count 1x 100 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401129-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Ia3; Ia-3; H-2Ea; H2-Ea; AI323765; I-Ealpha; E-alpha-f; MHC-H2-Ea
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DPB1
Gene ID
3115 (HLA-DP) & 3122 (HLA-DR)
NCBI Gene ID
347270 (HLA-DP); 520048 (HLA-DR)
UniProt
P04440 (HLA-DP); P01903 (HLA-DR)
Swiss Prot
P04440 (HLA-DP) & P01903 (HLA-DR)
Host
Mouse
Species Reactivity
Human
Reactivity
MHC-II
Immunogen
Human REH cells
Target Antigen
MHC-II
Clonality
Monoclonal
Clone
Bra-14
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Immunology, MHC antigens
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
36 kDa (? chain) and 27 kDa (? chain)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG3, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL?

The catalog number for MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL is BNC401129-100.

What sizes are available for MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL?

MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL in stock?

MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL?

MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL?

The safety data sheet for MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MHC II (HLA-DP) (beta chain) (Bra-14), CF640R conjugate, 0.1mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lympho

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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