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Product details

MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL

Catalog number BNC471129-500

Price for BNC471129-500

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Size / count 1x 500 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471129-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Ia3; Ia-3; H-2Ea; H2-Ea; AI323765; I-Ealpha; E-alpha-f; MHC-H2-Ea
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DPB1
Gene ID
3115 (HLA-DP) & 3122 (HLA-DR)
NCBI Gene ID
347270 (HLA-DP); 520048 (HLA-DR)
UniProt
P04440 (HLA-DP); P01903 (HLA-DR)
Swiss Prot
P04440 (HLA-DP) & P01903 (HLA-DR)
Host
Mouse
Species Reactivity
Human
Reactivity
MHC-II
Immunogen
Human REH cells
Target Antigen
MHC-II
Clonality
Monoclonal
Clone
Bra-14
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Immunology, MHC antigens
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
36 kDa (? chain) and 27 kDa (? chain)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG3, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL?

The catalog number for MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL is BNC471129-500.

What sizes are available for MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL?

MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL in stock?

MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL?

MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e102e8e/msds/bnc471129-500.pdf.

What is MHC II (HLA-DP) (beta chain) (Bra-14), CF647 conjugate, 0.1mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lympho

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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