Milk Fat Globulin (MFG-06), CF488A conjugate, 0.1mg/mL

About this product

Recognizes a protein of 40-45 kDa, identified as human milk fat globule membrane protein (HMFG) . HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC880227-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Breast epithelial antigen BA46; EDIL1; HMFG; Lactadherin; Lactadherin precursor; Medin; MFGE8; MFGM; Milk fat globule-EGF factor 8 (MFG-E8)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

MFGE8

Gene ID

4240

NCBI Gene ID

3745

UniProt

Q08431

Swiss Prot

Q08431

Host

Mouse

Species Reactivity

Human

Reactivity

Milk-Fat-Globulin

Immunogen

Human milk fat globule membrane preparation

Target Antigen

Milk-Fat-Globulin

Clonality

Monoclonal

Clone

MFG-06

Type

Primary

Source

Animal

Origin

Animal

Applications

IF (published) |IHC, FFPE (verified) |WB (published)

Positive Control

Normal breast or breast carcinoma

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

45 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Mol Endocrinol (2010) 24(2): 359-369. (WB) Lab Invest (2014) 94:1260-1272. (IHC, FFPE; IF) Exp Cell Res (2020) 392(1): 112013. (IF)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF488A