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Product details

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL

Catalog number BNC941130-500

Price for BNC941130-500

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Size / count 1x 500 µL

About this product

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941130-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM) ; Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCAM
Gene ID
4162
NCBI Gene ID
599039
UniProt
P43121
Swiss Prot
P43121
Host
Mouse
Species Reactivity
Human
Reactivity
CD146|MCAM|MUC18|Mucin 18
Immunogen
Recombinant human MUC18 protein
Target Antigen
CD146 | MCAM | MUC18 | Mucin 18
Clonality
Monoclonal
Clone
MUC18/1130
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
A-375, HUV-EC or HeLa Cells. Tonsil or Melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
130 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL?

The catalog number for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL is BNC941130-500.

What sizes are available for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL?

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL in stock?

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL?

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MUC18 / Mucin 18 / CD146 (MUC18/1130), CF594 conjugate, 0.1mg/mL used for?

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metast

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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