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Product details

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL

Catalog number BNC471130-100

Price for BNC471130-100

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Size / count 1x 100 µL

About this product

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471130-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM) ; Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCAM
Gene ID
4162
NCBI Gene ID
599039
UniProt
P43121
Swiss Prot
P43121
Host
Mouse
Species Reactivity
Human
Reactivity
CD146|MCAM|MUC18|Mucin 18
Immunogen
Recombinant human MUC18 protein
Target Antigen
CD146 | MCAM | MUC18 | Mucin 18
Clonality
Monoclonal
Clone
MUC18/1130
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
A-375, HUV-EC or HeLa Cells. Tonsil or Melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
130 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL?

The catalog number for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL is BNC471130-100.

What sizes are available for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL?

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL in stock?

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL?

MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1002d1/msds/bnc471130-100.pdf.

What is MUC18 / Mucin 18 / CD146 (MUC18/1130), CF647 conjugate, 0.1mg/mL used for?

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metast

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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