MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL

Catalog number BNC040676-500

Price for BNC040676-500

Size / count 1x 500 µL

About this product

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040676-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM) ; Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MCAM
Gene ID: 4162
NCBI Gene ID: 599039
UniProt: P43121
Swiss Prot: P43121
Host: Mouse
Species Reactivity: Human
Reactivity: CD146|MCAM|MUC18|Mucin 18
Immunogen: Recombinant human MUC18 protein
Target Antigen: CD146 | MCAM | MUC18 | Mucin 18
Clonality: Monoclonal
Clone: OJ79c
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |IF (published) |ELISA (published)
Field of Research: Cancer, Mucins
Positive Control: A-375, HUV-EC or HeLa Cells. Tonsil or Melanoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 130 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Microvascular Res (2009)78(3): 325-331. (ELISA) Stem Cells (2008) 26: 2408-2418. (Flow) Stem Cells and Development (2017) 26(13): 964. (IF)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL?

The catalog number for MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL is BNC040676-500.

What sizes are available for MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL?

MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL in stock?

MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL?

MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL?

The safety data sheet for MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.