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Product details

Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL

Catalog number BNC680845-500

Price for BNC680845-500

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Size / count 1x 500 µL

About this product

In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. Thealpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC680845-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MUC1
Gene ID
4582
NCBI Gene ID
89603
UniProt
P15941
Swiss Prot
P15941
Host
Mouse
Species Reactivity
Human
Reactivity
CD227|EMA|Episialin|Mucin 1
Immunogen
Human milk-fat globule membranes (HMFGM)
Target Antigen
CD227 | EMA | Episialin | Mucin 1
Clonality
Monoclonal
Clone
MUC1/845
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
265-400 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL?

The catalog number for Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL is BNC680845-500.

What sizes are available for Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL?

Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL in stock?

Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL?

Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ae061270361e108dfa/msds/bnc680845-500.pdf.

What is Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL used for?

In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. Thealpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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