PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL

Catalog number BNC742002-100

Price for BNC742002-100

Size / count 1x 100 µL

About this product

PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742002-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD279; CD279 antigen; PD1; PDCD1; Programmed cell death 1; Programmed cell death protein 1; Systemic lupus erythematosus susceptibility 2 (SLEB2)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: 18566
NCBI Gene ID: 5024
UniProt: Q02242
Swiss Prot: Q02242
Host: Rat
Species Reactivity: Mouse
Reactivity: PD1
Immunogen: PDCD1 transfected BHK cells
Target Antigen: PD1
Clonality: Monoclonal
Clone: RMP1-14
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Positive Control: Spleen, Thymus or Lymph Node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: ~50-55 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2005) 175:1586-1592. (Flow; functional studies) Cancer Res (2014) 74(14): 3652-8. (functional studies) Cancer Discov (2017) 7(7): 694-703. (functional studies)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL?

The catalog number for PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL is BNC742002-100.

What sizes are available for PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL?

PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL in stock?

PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL?

PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL?

The safety data sheet for PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102525/msds/bnc742002-100.pdf.

What is PD1, Mouse (RMP1-14), CF740 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.