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Product details

Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0630-500

Price for BNCB0630-500

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Size / count 1x 500 µL

About this product

MAb VU-2G7 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of VU-2G7 has not been established with epitope fingerprinting. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0630-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MUC1
Gene ID
4582
NCBI Gene ID
89603
UniProt
P15941
Swiss Prot
P15941
Host
Mouse
Species Reactivity
Human
Reactivity
CD227|EMA|Episialin|Mucin 1
Immunogen
Synthetic glycosylated MUC1 60mer tandem repeat NH2- (HGVTSAPDT (GalNAc) RPAPGSTAPPAHG) 3- COOH, conjugated to bovine serum albumin
Target Antigen
CD227 | EMA | Episialin | Mucin 1
Clonality
Monoclonal
Clone
VU-2G7
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |IHC, FFPE (published) |ELISA (published)
Field of Research
Cancer, Mucins
Positive Control
MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
265-400 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. ACS Omega (2017) 2 (11), 7493-7505. (ELISA, Flow) Arch Dermatol Res (2003) 295:146-154. (immunohistochemistry)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL?

The catalog number for Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL is BNCB0630-500.

What sizes are available for Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL?

Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL in stock?

Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL?

Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1003a1/msds/bncb0630-500.pdf.

What is Mucin 1 / EMA / Episialin / CD227 (VU-2G7), Biotin conjugate, 0.1mg/mL used for?

MAb VU-2G7 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of VU-2G7 has not been established with epitope fingerprinting. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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