Product details

Mucin 3 (M3.1), 0.2mg/mL

Catalog number BNUB0990-500

Price for BNUB0990-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3) . Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3) . The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB0990-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DOM; PCWH; SOX10; SRY (sex determining region Y) box 10; SRY box containing gene 10; SRY related HMG box gene 10; Waardenburg syndrome type 2E (WS2E) ; WS4; Waardenburg syndrome type 4C (WS4C)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MUC3A
Gene ID: 4584 & 57876
NCBI Gene ID: 744422 & 744530
UniProt: Q02505; Q9H195
Swiss Prot: Q02505 & Q9H195
Host: Mouse
Species Reactivity: Human
Reactivity: Mucin 3
Immunogen: A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
Target Antigen: Mucin 3
Clonality: Monoclonal
Clone: M3.1
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Mucins
Positive Control: LS174T cells or colon carcinoma and normal colon tissue.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 1100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Mucin 3 (M3.1), 0.2mg/mL?

The catalog number for Mucin 3 (M3.1), 0.2mg/mL is BNUB0990-500.

What sizes are available for Mucin 3 (M3.1), 0.2mg/mL?

Mucin 3 (M3.1), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Mucin 3 (M3.1), 0.2mg/mL in stock?

Mucin 3 (M3.1), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Mucin 3 (M3.1), 0.2mg/mL?

Mucin 3 (M3.1), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Mucin 3 (M3.1), 0.2mg/mL?

Estimated delivery time for Mucin 3 (M3.1), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Mucin 3 (M3.1), 0.2mg/mL?

The safety data sheet for Mucin 3 (M3.1), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101f91/msds/bnub0990-500.pdf.

What is Mucin 3 (M3.1), 0.2mg/mL used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.