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Product details

Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL

Catalog number BNC470990-500

Price for BNC470990-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3) . Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3) . The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470990-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
DOM; PCWH; SOX10; SRY (sex determining region Y) box 10; SRY box containing gene 10; SRY related HMG box gene 10; Waardenburg syndrome type 2E (WS2E) ; WS4; Waardenburg syndrome type 4C (WS4C)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MUC3A
Gene ID
4584 & 57876
NCBI Gene ID
744422 & 744530
UniProt
Q02505; Q9H195
Swiss Prot
Q02505 & Q9H195
Host
Mouse
Species Reactivity
Human
Reactivity
Mucin 3
Immunogen
A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
Target Antigen
Mucin 3
Clonality
Monoclonal
Clone
M3.1
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
LS174T cells or colon carcinoma and normal colon tissue.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
1100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL?

The catalog number for Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL is BNC470990-500.

What sizes are available for Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL?

Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL in stock?

Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL?

Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ab061270361e107ae9/msds/bnc470990-500.pdf.

What is Mucin 3 (M3.1), CF647 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3) . Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in br

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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