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Product details

Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL

Catalog number BNC040756-500

Price for BNC040756-500

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Size / count 1x 500 µL

About this product

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H) . Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC040756-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
NEFH; Neurofilament H; Neurofilament Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; NF-H; NF200
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NEFH
Gene ID
4744
NCBI Gene ID
198760
UniProt
P12036
Swiss Prot
P12036
Host
Mouse
Species Reactivity
Chicken, Human, Mouse, Pig, Rat
Reactivity
Neurofilament
Immunogen
Recombinant human neurofilament heavy sub-unit (RT-97) & light sub-unit (NR-4)
Target Antigen
Neurofilament
Clonality
Monoclonal
Clone
NF421 + NFL/736
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton, Neuroscience
Positive Control
Brain, Neuroblastoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
200 kDa & 68 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL?

The catalog number for Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL is BNC040756-500.

What sizes are available for Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL?

Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL in stock?

Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL?

Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Neurofilament (H+L) (NF421 + NFL736), CF405S conjugate, 0.1mg/mL used for?

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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