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Product details

NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL

Catalog number BNC400890-100

Price for BNC400890-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC400890-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor (NGFR) ; p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NGFR
Gene ID
4804
NCBI Gene ID
415768; 681726
UniProt
P08138
Swiss Prot
P08138
Host
Mouse
Species Reactivity
Baboon, Cat, Ferret, Human, Monkey, Rabbit
Reactivity
NGFR
Immunogen
NGFR from A875 melanoma cells
Target Antigen
NGFR
Clonality
Monoclonal
Clone
NGFR5
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Signal transduction
Positive Control
Melanoma|Neuronal axons, Schwann cells, and perineural cells of peripheral nerves|Soma and axons of sensory neurons, and ganglionic satellite cells|Tumors of nerve sheath differentiation, Schwannoma, Neurofibroma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
75 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL?

The catalog number for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL is BNC400890-100.

What sizes are available for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL?

NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL in stock?

NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL?

NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL?

The safety data sheet for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NGFR (Nerve Growth Factor Receptor) (NGFR5), CF640R conjugate, 0.1mg/mL used for?

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino aci

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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