NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL

Catalog number BNC470890-500

Price for BNC470890-500

Size / count 1x 500 µL

About this product

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470890-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor (NGFR) ; p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NGFR
Gene ID: 4804
NCBI Gene ID: 415768; 681726
UniProt: P08138
Swiss Prot: P08138
Host: Mouse
Species Reactivity: Baboon, Cat, Ferret, Human, Monkey, Rabbit
Reactivity: NGFR
Immunogen: NGFR from A875 melanoma cells
Target Antigen: NGFR
Clonality: Monoclonal
Clone: NGFR5
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Developmental biology, Signal transduction
Positive Control: Melanoma|Neuronal axons, Schwann cells, and perineural cells of peripheral nerves|Soma and axons of sensory neurons, and ganglionic satellite cells|Tumors of nerve sheath differentiation, Schwannoma, Neurofibroma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 75 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL?

The catalog number for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL is BNC470890-500.

What sizes are available for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL?

NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL in stock?

NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL?

NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL?

The safety data sheet for NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106ed5/msds/bnc470890-500.pdf.

What is NGFR (Nerve Growth Factor Receptor) (NGFR5), CF647 conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.