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Product details

NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL

Catalog number BNC940912-100

Price for BNC940912-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940912-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor (NGFR) ; p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NGFR
Gene ID
4804
NCBI Gene ID
415768; 681726
UniProt
P08138
Swiss Prot
P08138
Host
Mouse
Species Reactivity
Human, Non-human primates
Reactivity
NGFR
Immunogen
Recombinant human p75 NGFR protein
Target Antigen
NGFR
Clonality
Monoclonal
Clone
NTR/912
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Signal transduction
Positive Control
Melanoma|Neuronal axons, Schwann cells, and perineural cells of peripheral nerves|Soma and axons of sensory neurons, and ganglionic satellite cells|Tumors of nerve sheath differentiation, Schwannoma, Neurofibroma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
75 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL?

The catalog number for NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL is BNC940912-100.

What sizes are available for NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL?

NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL in stock?

NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL?

NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL?

The safety data sheet for NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NGFR (Nerve Growth Factor Receptor) (NTR/912), CF594 conjugate, 0.1mg/mL used for?

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurof

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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