NuMA (A73-B/D12), 0.2mg/mL

Catalog number BNUB0939-100

Price for BNUB0939-100

Size / count 1x 100 µL

About this product

Recognizes a phosphorylated protein of 228 kDa, identified as nuclear mitotic apparatus protein (NuMA) . Its epitope is resistant to phosphatases. NuMA is intra-nuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200 kDa during apoptosis. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 has been detected in patients with acute promyelocytic leukemia.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Specifications

Catalog number: BNUB0939-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Nuclear Mitotic Apparatus Protein 1; NuMA protein; NUMA1; SP-H antigen; Structural nuclear protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NUMA1
Gene ID: 4926
NCBI Gene ID: 325978
UniProt: Q14980
Swiss Prot: Q14980
Host: Mouse
Species Reactivity: Human
Reactivity: NuMA
Immunogen: Colon carcinoma 174T cells
Target Antigen: NuMA
Clonality: Monoclonal
Clone: A73-B/D12
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Cell cycle
Positive Control: Exponentially growing any cultured human cells. Tonsil or lymph node.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 228 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgM, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for NuMA (A73-B/D12), 0.2mg/mL?

The catalog number for NuMA (A73-B/D12), 0.2mg/mL is BNUB0939-100.

What sizes are available for NuMA (A73-B/D12), 0.2mg/mL?

NuMA (A73-B/D12), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is NuMA (A73-B/D12), 0.2mg/mL in stock?

NuMA (A73-B/D12), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NuMA (A73-B/D12), 0.2mg/mL?

NuMA (A73-B/D12), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for NuMA (A73-B/D12), 0.2mg/mL?

Estimated delivery time for NuMA (A73-B/D12), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NuMA (A73-B/D12), 0.2mg/mL?

The safety data sheet for NuMA (A73-B/D12), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e101221/msds/bnub0939-100.pdf.

What is NuMA (A73-B/D12), 0.2mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.