P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL

Catalog number BNC040043-500

Price for BNC040043-500

Size / count 1x 500 µL

About this product

This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma) . In ELISA, MAb WA-1 is useful either as a solid phase or for detection of p21 protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040043-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Activating Fragment 1; CAP20; CDK-interacting protein 1; CDKI; CDKN1; CDKN1A; CIP1; Cyclin-dependent kinase inhibitor 1A (p21; Cip1) ; DNA Synthesis Inhibitor; MDA6; Melanoma Differentiation Associated Protein 6; p21Cip1/Waf1; PIC1; SDI1; SLC12A9; Wild type p53 activated fragment 1 (WAF1)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CDKN1A
Gene ID: 1026
NCBI Gene ID: 370771
UniProt: P38936
Swiss Prot: P38936
Host: Mouse
Species Reactivity: Chimpanzee, Human, Monkey, Mouse, Rat
Reactivity: P21|WAF1
Immunogen: Human recombinant p21 protein
Target Antigen: p21 | WAF1
Clonality: Monoclonal
Clone: WA-1
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (published) |IF (published) |IHC, FFPE (verified) |WB (published)
Field of Research: Cell cycle, Tumor suppressors
Positive Control: HeLa Cells. Skin, colon, or breast carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 21 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (2001) 276(14): 11143-11150. (Flow, intracellular; IF) EMBO J (2002) 21:6771-6780. (WB)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL?

The catalog number for P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL is BNC040043-500.

What sizes are available for P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL?

P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL in stock?

P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL?

P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL?

The safety data sheet for P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e10015a/msds/bnc040043-500.pdf.

What is P21 / WAF1 (WA-1), CF405S conjugate, 0.1mg/mL used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.