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Product details

P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL

Catalog number BNC680043-100

Price for BNC680043-100

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Size / count 1x 100 µL

About this product

This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma) . In ELISA, MAb WA-1 is useful either as a solid phase or for detection of p21 protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC680043-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Activating Fragment 1; CAP20; CDK-interacting protein 1; CDKI; CDKN1; CDKN1A; CIP1; Cyclin-dependent kinase inhibitor 1A (p21; Cip1) ; DNA Synthesis Inhibitor; MDA6; Melanoma Differentiation Associated Protein 6; p21Cip1/Waf1; PIC1; SDI1; SLC12A9; Wild type p53 activated fragment 1 (WAF1)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CDKN1A
Gene ID
1026
NCBI Gene ID
370771
UniProt
P38936
Swiss Prot
P38936
Host
Mouse
Species Reactivity
Chimpanzee, Human, Monkey, Mouse, Rat
Reactivity
P21|WAF1
Immunogen
Human recombinant p21 protein
Target Antigen
p21 | WAF1
Clonality
Monoclonal
Clone
WA-1
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (published) |IF (published) |IHC, FFPE (verified) |WB (published)
Field of Research
Cell cycle, Tumor suppressors
Positive Control
HeLa Cells. Skin, colon, or breast carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
21 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (2001) 276(14): 11143-11150. (Flow, intracellular; IF) EMBO J (2002) 21:6771-6780. (WB)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL?

The catalog number for P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL is BNC680043-100.

What sizes are available for P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL?

P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL in stock?

P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL?

P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL?

The safety data sheet for P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109c84/msds/bnc680043-100.pdf.

What is P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL used for?

This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a va

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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