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Product details

P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1237-100

Price for BNCB1237-100

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Size / count 1x 100 µL

About this product

Recognizes a 27 kDa protein, identified as the p27/Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27/Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF-beta-induced G1 arrest. p27/Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27/Kip1 and is excellent for staining of formalin-fixed tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1237-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CDKN1B, CDKN4, Cyclin Dependent Kinase Inhibitor 1B, Cyclin-dependent kinase inhibitor p27 Kip1, KIP1, MEN1B, MEN4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CDKN1B
Gene ID
1027
NCBI Gene ID
238990
UniProt
P46527
Swiss Prot
P46527
Host
Mouse
Species Reactivity
Human, Monkey, Mouse, Rat
Reactivity
KIP1|p27
Immunogen
Mouse recombinant p27 protein (DCS-72.F6) ; Recombinant human CDKN1B protein (KIP1/769)
Target Antigen
KIP1 | p27
Clonality
Monoclonal
Clone
DCS-72.F6 KIP1/769
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cell cycle, Tumor suppressors
Positive Control
ZR75, T47D, SK-BR-3, MDA-MB-231, HeLa or MCF7 cells. Tonsil, Breast, Cervical or Colon Carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
25-26 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL?

The catalog number for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL is BNCB1237-100.

What sizes are available for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL?

P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL in stock?

P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL?

P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL?

The safety data sheet for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101611/msds/bncb1237-100.pdf.

What is P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), Biotin conjugate, 0.1mg/mL used for?

Recognizes a 27 kDa protein, identified as the p27/Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27/Kip1 functions as a negative regulator of G1 progression and ha

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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