P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL

Catalog number BNC941237-500

Price for BNC941237-500

Size / count 1x 500 µL

About this product

Recognizes a 27 kDa protein, identified as the p27/Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27/Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF-beta-induced G1 arrest. p27/Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27/Kip1 and is excellent for staining of formalin-fixed tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941237-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CDKN1B, CDKN4, Cyclin Dependent Kinase Inhibitor 1B, Cyclin-dependent kinase inhibitor p27 Kip1, KIP1, MEN1B, MEN4
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CDKN1B
Gene ID: 1027
NCBI Gene ID: 238990
UniProt: P46527
Swiss Prot: P46527
Host: Mouse
Species Reactivity: Human, Monkey, Mouse, Rat
Reactivity: KIP1|p27
Immunogen: Mouse recombinant p27 protein (DCS-72.F6) ; Recombinant human CDKN1B protein (KIP1/769)
Target Antigen: KIP1 | p27
Clonality: Monoclonal
Clone: DCS-72.F6 KIP1/769
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cell cycle, Tumor suppressors
Positive Control: ZR75, T47D, SK-BR-3, MDA-MB-231, HeLa or MCF7 cells. Tonsil, Breast, Cervical or Colon Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 25-26 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL?

The catalog number for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL is BNC941237-500.

What sizes are available for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL?

P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL in stock?

P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL?

P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL?

The safety data sheet for P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e101194/msds/bnc941237-500.pdf.

What is P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), CF594 conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.