P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL

Catalog number BNC680723-500

Price for BNC680723-500

Size / count 1x 500 µL

About this product

Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. Its epitope maps within the N-terminus (aa 20-25) of p53 oncoprotein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC680723-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Antigen NY-CO-13, BCC7, Cellular Tumor Antigen p53, LFS1, TP53, Transformation Related Protein 53 (TRP53), Tumor Protein p53, Tumor Suppressor p53
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TP53
Gene ID: 7157
NCBI Gene ID: 654481
UniProt: P04637
Swiss Prot: P04637
Host: Mouse
Species Reactivity: Cow, Human, Monkey
Reactivity: P53 Tumor Suppressor Protein
Immunogen: Recombinant human wild-type p53 protein (BP53-12) & Recombinant human wild type p53 protein expressed in E. coli (DO-7)
Target Antigen: p53 Tumor Suppressor Protein
Clonality: Monoclonal
Clone: BP53-12 DO-7
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Apoptosis, Tumor suppressors
Positive Control: MDA-MB-231 Cells. Breast or Colon carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 53 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL?

The catalog number for P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL is BNC680723-500.

What sizes are available for P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL?

P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL in stock?

P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL?

P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL?

The safety data sheet for P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104a74/msds/bnc680723-500.pdf.

What is P53 (BP53-12 + DO-7), CF568 conjugate, 0.1mg/mL used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.