PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL

Catalog number BNC471166-500

Price for BNC471166-500

Size / count 1x 500 µL

About this product

Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471166-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AN2; Aniridia type II protein; Oculorhombin; Paired box gene 6 (aniridia keratitis) ; Paired box homeotic gene 6; Paired box protein Pax-6; Sey; WAGR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PAX6
Gene ID: 5080
NCBI Gene ID: 611376
UniProt: P26367
Swiss Prot: P26367
Host: Mouse
Species Reactivity: Human
Reactivity: PAX6
Immunogen: Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein
Target Antigen: PAX6
Clonality: Monoclonal
Clone: PAX6/1166
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Developmental biology, Transcription factors
Positive Control: Pancreas, Cerebellum or Stomach
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 47 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL?

The catalog number for PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL is BNC471166-500.

What sizes are available for PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL?

PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL in stock?

PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL?

PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL?

The safety data sheet for PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b5061270361e10b209/msds/bnc471166-500.pdf.

What is PAX6 (PAX6/1166), CF647 conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.