PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL

Catalog number BNC040498-100

Price for BNC040498-100

Size / count 1x 100 µL

About this product

Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040498-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AN2; Aniridia type II protein; Oculorhombin; Paired box gene 6 (aniridia keratitis) ; Paired box homeotic gene 6; Paired box protein Pax-6; Sey; WAGR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PAX6
Gene ID: 5080
NCBI Gene ID: 611376
UniProt: P26367
Swiss Prot: P26367
Host: Mouse
Species Reactivity: Chicken, Human, Mouse, Rat
Reactivity: PAX6
Immunogen: Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein
Target Antigen: PAX6
Clonality: Monoclonal
Clone: PAX6/498
Type: Primary
Source: Animal
Origin: Animal
Applications: WB (verified)
Field of Research: Developmental biology, Transcription factors
Positive Control: Pancreas or Cerebellum
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 47 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL?

The catalog number for PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL is BNC040498-100.

What sizes are available for PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL?

PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL in stock?

PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL?

PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL?

The safety data sheet for PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PAX6 (PAX6/498), CF405S conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.