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Product details

PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0922-100

Price for BNCB0922-100

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Size / count 1x 100 µL

About this product

PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligands PD-L1 or PD-L2 has a suppressive effect on the immune system, inhibition of the PD-1/PD-L1 pathway is a major strategy of immune-oncology therapies. PD-L1 is upregulated in certain cancers, and blocking PD-1 or PD-L1 can inhibit cancer growth. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0922-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD279; hPD-1; hSLE1; PD1; PDCD1; Programmed Cell Death Protein 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PDCD1
Gene ID
5133
NCBI Gene ID
158297
UniProt
Q15116
Swiss Prot
Q15116
Host
Mouse
Species Reactivity
Human
Reactivity
CD279|PD1|PDCD1
Immunogen
Recombinant full-length human PDCD1 protein
Target Antigen
CD279 | PD1 | PDCD1
Clonality
Monoclonal
Clone
PDCD1/922
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Apoptosis, Cancer, Cancer immunotherapy/immune checkpoint
Positive Control
TY cells or Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
55 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL?

The catalog number for PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL is BNCB0922-100.

What sizes are available for PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL?

PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL in stock?

PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL?

PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL?

The safety data sheet for PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PD1 / PDCD1 / CD279 (PDCD1/922), Biotin conjugate, 0.1mg/mL used for?

PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligan

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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