Product details
Catalog number BNC400922-500
Price for BNC400922-500
Size / count 1x 500 µL
PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligands PD-L1 or PD-L2 has a suppressive effect on the immune system, inhibition of the PD-1/PD-L1 pathway is a major strategy of immune-oncology therapies. PD-L1 is upregulated in certain cancers, and blocking PD-1 or PD-L1 can inhibit cancer growth. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for PD1 / PDCD1 / CD279 (PDCD1/922), CF640R conjugate, 0.1mg/mL is BNC400922-500.
PD1 / PDCD1 / CD279 (PDCD1/922), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
PD1 / PDCD1 / CD279 (PDCD1/922), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
PD1 / PDCD1 / CD279 (PDCD1/922), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for PD1 / PDCD1 / CD279 (PDCD1/922), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for PD1 / PDCD1 / CD279 (PDCD1/922), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e10094a/msds/bnc400922-500.pdf.
PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligan
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.