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Product details
Catalog number BNC800922-500
Price for BNC800922-500
Size / count 1x 500 µL
PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligands PD-L1 or PD-L2 has a suppressive effect on the immune system, inhibition of the PD-1/PD-L1 pathway is a major strategy of immune-oncology therapies. PD-L1 is upregulated in certain cancers, and blocking PD-1 or PD-L1 can inhibit cancer growth. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for PD1 / PDCD1 / CD279 (PDCD1/922), CF680 conjugate, 0.1mg/mL is BNC800922-500.
PD1 / PDCD1 / CD279 (PDCD1/922), CF680 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
PD1 / PDCD1 / CD279 (PDCD1/922), CF680 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
PD1 / PDCD1 / CD279 (PDCD1/922), CF680 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for PD1 / PDCD1 / CD279 (PDCD1/922), CF680 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for PD1 / PDCD1 / CD279 (PDCD1/922), CF680 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102a69/msds/bnc800922-500.pdf.
PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligan
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
