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Product details

PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0870-100

Price for BNCB0870-100

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Size / count 1x 100 µL

About this product

Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0870-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Alkaline phosphatase placental type|Alkaline phosphatase Regan Isozyme|ALP|Alp1|ALPP|Germ-cell alkaline phosphatase|nagao Isozyme|PALP|Placental alkaline phosphatase 1|placental heat-stable alkaline phosphatase|PLAP-1|PLAP1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ALPP
Gene ID
250
NCBI Gene ID
284255
UniProt
P05187
Swiss Prot
P05187
Host
Mouse
Species Reactivity
Human
Reactivity
PLAP
Immunogen
Recombinant full-length human ALPP protein
Target Antigen
PLAP
Clonality
Monoclonal
Clone
ALP/870
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Metabolism
Positive Control
HepG2 cells. Placenta or seminoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL?

The catalog number for PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL is BNCB0870-100.

What sizes are available for PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL?

PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL in stock?

PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL?

PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL?

The safety data sheet for PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PLAP (Placental Alkaline Phosphatase) (ALP/870), Biotin conjugate, 0.1mg/mL used for?

Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with g

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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