PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL

Catalog number BNC040874-500

Price for BNC040874-500

Size / count 1x 500 µL

About this product

Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040874-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Alkaline phosphatase placental type|Alkaline phosphatase Regan Isozyme|ALP|Alp1|ALPP|Germ-cell alkaline phosphatase|nagao Isozyme|PALP|Placental alkaline phosphatase 1|placental heat-stable alkaline phosphatase|PLAP-1|PLAP1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ALPP
Gene ID: 250
NCBI Gene ID: 284255
UniProt: P05187
Swiss Prot: P05187
Host: Mouse
Species Reactivity: Human
Reactivity: PLAP
Immunogen: Recombinant human PLAP protein
Target Antigen: PLAP
Clonality: Monoclonal
Clone: GM022
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Metabolism
Positive Control: HepG2 cells. Placenta or seminoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL?

The catalog number for PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL is BNC040874-500.

What sizes are available for PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL?

PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL in stock?

PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL?

PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL?

The safety data sheet for PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PLAP (Placental Alkaline Phosphatase) (GM022), CF405S conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.