PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL

Catalog number BNC940874-100

Price for BNC940874-100

Size / count 1x 100 µL

About this product

Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC940874-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Alkaline phosphatase placental type|Alkaline phosphatase Regan Isozyme|ALP|Alp1|ALPP|Germ-cell alkaline phosphatase|nagao Isozyme|PALP|Placental alkaline phosphatase 1|placental heat-stable alkaline phosphatase|PLAP-1|PLAP1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ALPP
Gene ID: 250
NCBI Gene ID: 284255
UniProt: P05187
Swiss Prot: P05187
Host: Mouse
Species Reactivity: Human
Reactivity: PLAP
Immunogen: Recombinant human PLAP protein
Target Antigen: PLAP
Clonality: Monoclonal
Clone: GM022
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Metabolism
Positive Control: HepG2 cells. Placenta or seminoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL?

The catalog number for PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL is BNC940874-100.

What sizes are available for PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL?

PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL in stock?

PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL?

PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL?

The safety data sheet for PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PLAP (Placental Alkaline Phosphatase) (GM022), CF594 conjugate, 0.1mg/mL used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.