Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL — image 1 of 2

Product details

Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL

Catalog number BNC040444-500

Price for BNC040444-500

Size / count 1x 500 µL

About this product

By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. It reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, malignant melanoma, and angiomyolipoma (PEComa) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040444-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PMEL
Gene ID: 6490
NCBI Gene ID: 95972
UniProt: P40967
Swiss Prot: P40967
Host: Mouse
Species Reactivity: Human
Reactivity: Gp100|Pmel17|SILV
Immunogen: Extract of pigmented melanoma metastases from lymph nodes
Target Antigen: gp100 | Pmel17 | SILV
Clonality: Monoclonal
Clone: HMB45
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer
Positive Control: SK-MEL-28 cells or Melanoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90-100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL?

The catalog number for Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL is BNC040444-500.

What sizes are available for Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL in stock?

Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100516/msds/bnc040444-500.pdf.

What is Pmel17 / gp100 / SILV (HMB45), CF405S conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.