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Product details

Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL

Catalog number BNC680226-100

Price for BNC680226-100

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Size / count 1x 100 µL

About this product

By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. It reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC680226-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PMEL
Gene ID
6490
NCBI Gene ID
95972
UniProt
P40967
Swiss Prot
P40967
Host
Mouse
Species Reactivity
Horse, Human
Reactivity
Gp100|Pmel17|SILV
Immunogen
Membranes from a human melanoma metastasis
Target Antigen
gp100 | Pmel17 | SILV
Clonality
Monoclonal
Clone
NKI-beteb
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (published) |IF (published) |IHC, frozen (published) |ELISA (published) |IHC, FFPE (verified) |IP (published)
Field of Research
Cancer
Positive Control
SK-MEL-28 cells or Melanoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
90-100 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Am J Pathol (1988) 130(1): 179. (mAb characterization; IHC, FFPE; IF; ELISA; IP; WB) Am J Pathol (1993) 143(6): 1579. (IHC, frozen; IF) J Biol Chem (2004) 279(27): 28330-28338. (epitope mapping; IP; reports that NKI-beteb does not work well for WB) Exp Dermatol (2010) 19(8): e282-e285. (IF; Flow, intracellular)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL?

The catalog number for Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL is BNC680226-100.

What sizes are available for Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL in stock?

Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b7061270361e10bb3a/msds/bnc680226-100.pdf.

What is Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL used for?

By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. It reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stai

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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