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Product details

Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL

Catalog number BNUB0783-100

Price for BNUB0783-100

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Size / count 1x 100 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. PMEL 17, also designated gp100, ME20-M, or ME20-S, is classified as a melanocyte differentiation antigen. It is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. It is a highly glycosylated, secreted protein that is the product of proteolytic cleavage.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB0783-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PMEL
Gene ID
6490
NCBI Gene ID
95972
UniProt
P40967
Swiss Prot
P40967
Host
Mouse
Species Reactivity
Human
Reactivity
Gp100|Pmel17|SILV
Immunogen
Recombinant human SILV protein
Target Antigen
gp100 | Pmel17 | SILV
Clonality
Monoclonal
Clone
PMEL/783
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer
Positive Control
SK-MEL-28 cells or Melanoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
90-100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL?

The catalog number for Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL is BNUB0783-100.

What sizes are available for Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL in stock?

Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL?

Estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL?

The safety data sheet for Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e10104a/msds/bnub0783-100.pdf.

What is Pmel17 / gp100 / SILV (PMEL/783), 0.2mg/mL used for?

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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