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Product details

Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL

Catalog number BNC040783-500

Price for BNC040783-500

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Size / count 1x 500 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. PMEL 17, also designated gp100, ME20-M, or ME20-S, is classified as a melanocyte differentiation antigen. It is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. It is a highly glycosylated, secreted protein that is the product of proteolytic cleavage.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC040783-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PMEL
Gene ID
6490
NCBI Gene ID
95972
UniProt
P40967
Swiss Prot
P40967
Host
Mouse
Species Reactivity
Human
Reactivity
Gp100|Pmel17|SILV
Immunogen
Recombinant human SILV protein
Target Antigen
gp100 | Pmel17 | SILV
Clonality
Monoclonal
Clone
PMEL/783
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer
Positive Control
SK-MEL-28 cells or Melanoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
90-100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL?

The catalog number for Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL is BNC040783-500.

What sizes are available for Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL in stock?

Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e10055f/msds/bnc040783-500.pdf.

What is Pmel17 / gp100 / SILV (PMEL/783), CF405S conjugate, 0.1mg/mL used for?

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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