Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL — image 1 of 2

Product details

Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL

Catalog number BNC400783-100

Price for BNC400783-100

Size / count 1x 100 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. PMEL 17, also designated gp100, ME20-M, or ME20-S, is classified as a melanocyte differentiation antigen. It is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. It is a highly glycosylated, secreted protein that is the product of proteolytic cleavage.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400783-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PMEL
Gene ID: 6490
NCBI Gene ID: 95972
UniProt: P40967
Swiss Prot: P40967
Host: Mouse
Species Reactivity: Human
Reactivity: Gp100|Pmel17|SILV
Immunogen: Recombinant human SILV protein
Target Antigen: gp100 | Pmel17 | SILV
Clonality: Monoclonal
Clone: PMEL/783
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer
Positive Control: SK-MEL-28 cells or Melanoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90-100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL?

The catalog number for Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL is BNC400783-100.

What sizes are available for Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL in stock?

Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Pmel17 / gp100 / SILV (PMEL/783), CF640R conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.