Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL — image 1 of 2

Product details

Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL

Catalog number BNC470783-500

Price for BNC470783-500

Size / count 1x 500 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. PMEL 17, also designated gp100, ME20-M, or ME20-S, is classified as a melanocyte differentiation antigen. It is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. It is a highly glycosylated, secreted protein that is the product of proteolytic cleavage.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470783-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PMEL
Gene ID: 6490
NCBI Gene ID: 95972
UniProt: P40967
Swiss Prot: P40967
Host: Mouse
Species Reactivity: Human
Reactivity: Gp100|Pmel17|SILV
Immunogen: Recombinant human SILV protein
Target Antigen: gp100 | Pmel17 | SILV
Clonality: Monoclonal
Clone: PMEL/783
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer
Positive Control: SK-MEL-28 cells or Melanoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90-100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL?

The catalog number for Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL is BNC470783-500.

What sizes are available for Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL in stock?

Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c1cb/msds/bnc470783-500.pdf.

What is Pmel17 / gp100 / SILV (PMEL/783), CF647 conjugate, 0.1mg/mL used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.