PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL

Catalog number BNC401236-100

Price for BNC401236-100

Size / count 1x 100 µL

About this product

The epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood calcium levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH) ; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC401236-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: HPTH; Parathormone; Parathyrin; Parathyroid hormone 1 (PTH1) ; Parathyroid hormone (PTH)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PTH
Gene ID: 5741
NCBI Gene ID: 37045
UniProt: P01270
Swiss Prot: P01270
Host: Mouse
Species Reactivity: Human
Reactivity: PTH
Immunogen: Synthetic peptide corresponding to amino acids 1 to 34 of PTH conjugated to a carrier (3H9) ; Recombinant fragment (84 amino acid residues from C-terminus) of human PTH protein
Target Antigen: PTH
Clonality: Monoclonal
Clone: 3H9 PTH/1175
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Endocrinology
Positive Control: Human parathyroid gland carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 9 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL?

The catalog number for PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL is BNC401236-100.

What sizes are available for PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL?

PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL in stock?

PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL?

PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL?

The safety data sheet for PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.