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Product details
Catalog number BNC742248-100
Price for BNC742248-100
Size / count 1x 100 µL
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP) . In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF740 conjugate, 0.1mg/mL is BNC742248-100.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e10386f/msds/bnc742248-100.pdf.
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
