SUMO-1 (SM1/495), CF647 conjugate, 0.1mg/mL

About this product

This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC470495-100

Size / count

1x 100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

GAP-modifying protein 1; GMP1; OFC10; PIC1; SENP2; Sentrin 1; Small ubiquitin-related modifier 1; SMT3; SMT3 suppressor of mif two 3 homolog 1; SMT3C; SMT3H3; Ubiquitin homology domain protein PIC1; Ubiquitin Like 1; Ubiquitin like protein UBL1

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

SUMO1

Gene ID

7341

NCBI Gene ID

596171

UniProt

P63165

Swiss Prot

P63165

Host

Mouse

Species Reactivity

Human, Rat

Reactivity

SUMO 1

Immunogen

Recombinant human SUMO1 protein

Target Antigen

SUMO 1

Clonality

Monoclonal

Clone

SM1/495

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, intracellular|IF (verified) |IHC, FFPE (verified) |WB (verified)

Field of Research

Sumoylation

Positive Control

Breast carcinoma

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

11.5 kDa (Monomer) ; 90 kDa (Heteromer)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF647