TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL

Catalog number BNC040977-100

Price for BNC040977-100

Size / count 1x 100 µL

About this product

This MAb recognizes TGF beta 1, 2 and 3. Three TGF-betas have been identified in mammals. TGF-beta1, TGF-beta2 and TGF-beta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF-beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF-beta3 protein has approximately 80% identity to the mature region of both TGF-beta1 and TGF-beta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGF-beta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040977-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TGFB1
Gene ID: 7040 (beta1), 7042 (beta2) & 7043 (beta3)
NCBI Gene ID: 645227
UniProt: P01137 (beta1), P10600 (beta2); P61812 (beta3)
Swiss Prot: P01137 (beta1), P10600 (beta2) & P61812 (beta3)
Host: Mouse
Species Reactivity: Cow, Dog, Hamster, Human, Monkey, Mouse, Rat
Reactivity: TGF-Beta
Immunogen: Bovine TGF-beta2 protein
Target Antigen: TGF-Beta
Clonality: Monoclonal
Clone: 1D11.16.8
Type: Primary
Source: Animal
Origin: Animal
Applications: Functional studies (published) |IHC, FFPE (published)
Field of Research: Signal transduction
Positive Control: Salivary gland carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~13 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Biol Reproduct (1992) 46: 561-572. (IHC, FFPE) PLOS ONE 10(7): e0132786. (functional studies)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL?

The catalog number for TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL is BNC040977-100.

What sizes are available for TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL?

TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL in stock?

TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL?

TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL?

The safety data sheet for TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.