Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL

Catalog number BNC400023-100

Price for BNC400023-100

Size / count 1x 100 µL

About this product

MAb 2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400023-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AITD3; hTG; TDH3; Tg; Tgn
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TG
Gene ID: 7038
NCBI Gene ID: 654591
UniProt: P01266
Swiss Prot: P01266
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Reactivity: Thyroglobulin
Immunogen: Human thyroid follicular cells
Target Antigen: Thyroglobulin
Clonality: Monoclonal
Clone: 2H11
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: Thyroid
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 660 kDa (Dimeric Form)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL?

The catalog number for Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL is BNC400023-100.

What sizes are available for Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL?

Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL in stock?

Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL?

Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Thyroglobulin (2H11), CF640R conjugate, 0.1mg/mL used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.