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Product details

TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL

Catalog number BNC470408-100

Price for BNC470408-100

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Size / count 1x 100 µL

About this product

TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM) . An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470408-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HSMRK222, K222TA2, Protein MIG-5, SFD, Sorsby fundus dystrophy pseudo-inflammatory, TIMP metallopeptidase inhibitor 3, Tissue Inhibitor of Metalloproteinase 3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TIMP3
Gene ID
7078
NCBI Gene ID
644633 & 714168
UniProt
P35625
Swiss Prot
P35625
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Rat
Reactivity
TIMP3
Immunogen
The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in mouse and rat.
Target Antigen
TIMP3
Clonality
Polyclonal
Clone
PAb
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Extracellular matrix, Proteases
Positive Control
Placenta or breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~30 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

The catalog number for TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL is BNC470408-100.

What sizes are available for TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL in stock?

TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

The safety data sheet for TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ae061270361e108b3e/msds/bnc470408-100.pdf.

What is TIMP3 (Rabbit PAb), CF647 conjugate, 0.1mg/mL used for?

TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM) . An imbalance between MMPs and the associated TIMPs may play a

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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